BDBM165008 US9067917, 41::US9067917, 43::US9682971, 42

SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1F

InChI Key InChIKey=HHTSKRULZHVWQT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 165008   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM165008(US9067917, 41 | US9067917, 43 | US9682971, 42)
Affinity DataKi:  4.20nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM165008(US9067917, 41 | US9067917, 43 | US9682971, 42)
Affinity DataKi:  6.30nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM165008(US9067917, 41 | US9067917, 43 | US9682971, 42)
Affinity DataKi:  630nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent