BDBM167784 US9073922, 275::US9796708, Example 275

SMILES COc1ccc(F)cc1-c1c(cnc2[nH]c(cc12)C1CCN(CC(=O)N(C)C)CC1)C#N

InChI Key InChIKey=NDTXKBSFGOQMPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167784   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM167784(US9073922, 275 | US9796708, Example 275)
Affinity DataIC50: 90nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2019
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM167784(US9073922, 275 | US9796708, Example 275)
Affinity DataIC50: 90nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
US Patent