BDBM168714 US9079866, 92::US9079866, 93::US9745328, Compound 93::US9884878, Compound 93

SMILES N[C@H]1CCN(C1)S(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1

InChI Key InChIKey=HNVMXIICKHNIJC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 168714   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM168714(US9079866, 92 | US9079866, 93 | US9884878, Compoun...)
Affinity DataKi:  127nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM168714(US9079866, 92 | US9079866, 93 | US9884878, Compoun...)
Affinity DataKi:  127nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetFlap endonuclease 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM168714(US9079866, 92 | US9079866, 93 | US9884878, Compoun...)
Affinity DataKi:  127nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM168714(US9079866, 92 | US9079866, 93 | US9884878, Compoun...)
Affinity DataKi:  325nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent