BDBM175780 US9688683, 14::US9688683, 16

SMILES COc1ccc(cc1Cl)-c1nc(C)c2ccn(-c3ccc(cc3)C(O)=O)c2n1

InChI Key InChIKey=FATGHNMGPUMNFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175780   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM175780(US9688683, 14 | US9688683, 16)
Affinity DataIC50: <1.00E+3nMpH: 7.8 T: 2°CAssay Description:The test compound or water (control) is mixed with the human recombinant PDE4B1 enzyme (4.8 U) in a buffer consisting of 44.4 mM tris-HCl, 5.28 mM Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM175780(US9688683, 14 | US9688683, 16)
Affinity DataIC50: <1.00E+3nMpH: 7.8 T: 2°CAssay Description:The test compound or water (control) is mixed with the human recombinant PDE4B1 enzyme (4.8 U) in a buffer consisting of 44.4 mM tris-HCl, 5.28 mM Mg...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent