BDBM176384 US9688696, 100

SMILES CC(C)n1ncc2nc([nH]c12)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1cccc(F)c1

InChI Key InChIKey=GAOHECGKSJYJQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176384   

TargetDiacylglycerol O-acyltransferase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM176384(US9688696, 100)
Affinity DataIC50: 3.98E+3nMpH: 7.4 T: 2°CAssay Description:DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent