BDBM17643 (E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morpholin-4-yl)-1-oxopropan-2-yl]-2-oxopyrrolidin-3-yl]ethene-1-sulfonamide::CHEMBL220050::N-[(3S)-2-oxopyrrolidin-3-yl]sulfonamide, 1f
SMILES C[C@H](N1CC[C@H](NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O)C(=O)N1CCOCC1
InChI Key InChIKey=ACEFOQMQINFMRW-DYCFVMESSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 17643
Affinity DataKi: 4nM ΔG°: -11.3kcal/molepH: 7.4 T: 2°CAssay Description:The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 367nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataKi: 367nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.58E+5nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair