BDBM176554 US9120756, 16

SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key InChIKey=WVJARZWJWNGZDX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 176554   

LigandPNGBDBM176554(US9120756, 16)
Affinity DataKi:  0.200nMAssay Description:The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

LigandPNGBDBM176554(US9120756, 16)
Affinity DataKi:  0.300nM ΔG°:  -13.5kcal/moleT: 2°CAssay Description:The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

LigandPNGBDBM176554(US9120756, 16)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed