BDBM177124 US9120749, 490

SMILES COc1cc(cc(Cl)c1O)-c1ccc2ncc(C(=O)C3CC3)c(Nc3ccc(Cn4ccnc4)cc3)c2c1

InChI Key InChIKey=HFIRJBLPXDARCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177124   

TargetMaternal embryonic leucine zipper kinase(Human)
Oncotherapy Science

US Patent
LigandPNGBDBM177124(US9120749, 490)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent