BDBM177874 US9120791, Example 100

SMILES OC1CCn2c(C1)c(cc2-c1cc(F)ccc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)C(=O)N(c1ccccc1)c1ccc(O)cc1

InChI Key InChIKey=HUFKDCYVEJDPOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177874   

TargetApoptosis regulator Bcl-2(Mouse)
Les Laboratoires Servier

US Patent
LigandPNGBDBM177874(US9120791, Example 100)
Affinity DataIC50: 22nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent