BDBM177891 US9120791, Example 121::US9603854, 121

SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2ccncc12)c1cccc(F)c1

InChI Key InChIKey=HDDUGVRHHUZCJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177891   

TargetApoptosis regulator Bcl-2(Mouse)
Les Laboratoires Servier

US Patent
LigandPNGBDBM177891(US9120791, Example 121 | US9603854, 121)
Affinity DataIC50: 34nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM177891(US9120791, Example 121 | US9603854, 121)
Affinity DataIC50: 34nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent