BDBM177933 US9120797, 31

SMILES CN(C)C1(CCC2(CC1)NCCc1c2[nH]c2cc(F)ccc12)c1ccccc1

InChI Key InChIKey=HXDWGMGPWBSVQP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177933   

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandPNGBDBM177933(US9120797, 31)
Affinity DataKi:  6.90nM ΔG°:  -11.1kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM177933(US9120797, 31)
Affinity DataKi:  17nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent