BDBM17801 benzimidazole-acetamide, 29::methyl N-{6-[4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}methyl)phenoxy]-1H-1,3-benzodiazol-2-yl}carbamate

SMILES COC(=O)Nc1nc2ccc(Oc3ccc(CC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2[nH]1

InChI Key InChIKey=KCJAPLFLYYZXFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17801   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM17801(benzimidazole-acetamide, 29 | methyl N-{6-[4-({[2-...)
Affinity DataIC50:  16nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Gsk

LigandPNGBDBM17801(benzimidazole-acetamide, 29 | methyl N-{6-[4-({[2-...)
Affinity DataIC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed