BDBM179408 US9126973, 10

SMILES c1nc([nH]c1-c1cnc(nc1)-c1ccccc1)-c1cccnc1

InChI Key InChIKey=JYCLUMTXRWBELE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179408   

TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179408(US9126973, 10)
Affinity DataIC50:  79nMT: 2°CAssay Description:This assay essentially is available from Cayman Chemical Company as Catalog item #600007. The test data reported for the aforementioned Examples (H-P...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179408(US9126973, 10)
Affinity DataIC50:  13nMAssay Description:Inhibition of HPGDS (unknown origin) assessed as reduction in reduction in LPS-induced PGD2 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179408(US9126973, 10)
Affinity DataIC50:  13nMAssay Description:Inhibition of HPGDS (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHematopoietic prostaglandin D synthase(Homo sapiens (Human))
Cayman Chemical

US Patent
LigandPNGBDBM179408(US9126973, 10)
Affinity DataIC50:  21nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In DepthDetails US Patent