BDBM183611 US9145354, 275

SMILES COc1cc(ccc1C#N)C(=O)c1c(Cl)ccc([C@H](N[C@@H](C)CC(N)=O)C2CC2)c1F

InChI Key InChIKey=XKZIQGXZLOPEEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 183611   

TargetGenome polyprotein(HCV)
Astex Therapeutics

US Patent
LigandPNGBDBM183611(US9145354, 275)
Affinity DataIC50: 130nMT: 2°CAssay Description:The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent