BDBM18526 6-amino-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one::6-amino-4-trifluoromethylquinolin-2(1H)-one, 3

SMILES Nc1ccc2[nH]c(=O)cc(c2c1)C(F)(F)F

InChI Key InChIKey=LMXZMEMPGRLDIG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18526   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18526(6-amino-4-(trifluoromethyl)-1,2-dihydroquinolin-2-...)
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/mole IC50:  26nMpH: 7.4 T: 2°CAssay Description:The compounds were evaluated in a transcriptional activation assay with hAR in a mammalian cell background (CV-1) as the primary in vitro assay. Rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed