BDBM185819 US9163003, 31

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)[C@@H]1CCN(Cc2nc3ccccc(=O)c3[nH]2)C1=O

InChI Key InChIKey=NVYDBKBQXGPVQD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 185819   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Novartis

US Patent
LigandPNGBDBM185819(US9163003, 31)
Affinity DataIC50: 390nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Novartis

US Patent
LigandPNGBDBM185819(US9163003, 31)
Affinity DataIC50: 1.08E+3nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Novartis

US Patent
LigandPNGBDBM185819(US9163003, 31)
Affinity DataIC50: 1.90E+4nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Novartis

US Patent
LigandPNGBDBM185819(US9163003, 31)
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent