BDBM18620 2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl-17-oxa-6-azatetracyclo[8.8.0.0^{2,7}.0^{11,16}]octadeca-1(10),2(7),3,8,11,13,15-heptaen-18-ylidene]methyl}thiophene-3-carbonitrile::Nitrile, 14

SMILES COc1c(O)ccc2O\C(=C/c3sccc3C#N)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=UZIJLTBYAYIURJ-JAIQZWGSSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18620   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18620(2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl-17...)
Affinity DataIC50:  0.800nM EC50:  0.200nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed