BDBM186315 US9670142, A156 5-(6-chloro-benzoxazol-2-yl)-pyrimidine-2-carboxylic acid methyl-((1R,3S)-3-propionylamino-cyclopentyl)-amide

SMILES CCC(=O)N[C@H]1CC[C@H](C1)N(C)C(=O)c1ncc(cn1)-c1nc2ccc(Cl)cc2o1

InChI Key InChIKey=IQSVIOLGLNSTEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 186315   

TargetFatty acid synthase(Human)
Merck Patent

US Patent
LigandPNGBDBM186315(US9670142, A156 5-(6-chloro-benzoxazol-2-yl)-pyrim...)
Affinity DataIC50: 2.65E+4nMpH: 7.0 T: 2°CAssay Description:The biochemical FASN activity testing was performed as 384 well two-time-point kinetic fluorescence intensity assay format in Greiner low volume medi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent