BDBM18884 2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)phenyl]methyl}-3,5-dimethylphenoxy)acetic acid::CHEMBL112087::JMC496635 Compound 4::thyromimetic, 5a
SMILES CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)cc(c1O)-c1ccc(cc1)[N+]([O-])=O
InChI Key InChIKey=PBZAEAFSLYJVGD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 18884
Affinity DataIC50: 200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Affinity DataIC50: 35nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Antagonist activity at human TRalpha1More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha1 (hTRalpha1)More data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Antagonist activity at human TRbeta1More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair