BDBM189072 US9169260, 341

SMILES CC(C)S(=O)(=O)c1ccc(cc1)-c1cc(NC(=O)c2cnn3cccnc23)n(n1)-c1ccc(C)cc1

InChI Key InChIKey=UEDVKXDNDFTIMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189072   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM189072(US9169260, 341)
Affinity DataIC50: 1.00E+3nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent