BDBM189409 US9174969, JHE-01-129A

SMILES OC(=O)\C=C/C(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1cccc(Cl)c1

InChI Key InChIKey=FRRXOTYUJZBGQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 189409   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of South Florida

US Patent
LigandPNGBDBM189409(US9174969, JHE-01-129A)
Affinity DataIC50: 2.80E+3nMAssay Description:IC50 values for indoline Shp2 inhibitors of the present invention, as determined by in vitro phosphotyrosine phosphatase activity (DiFMUP) assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2016
Entry Details
US Patent