BDBM191144 US9181266, 6

SMILES COc1ccc(cc1)C(=O)C1CCN(CC(=O)NCc2nc3CCCCCc3c(=O)[nH]2)CC1

InChI Key InChIKey=KDEAARCPDWPBIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191144   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Novartis

US Patent
LigandPNGBDBM191144(US9181266, 6)
Affinity DataIC50: 353nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Novartis

US Patent
LigandPNGBDBM191144(US9181266, 6)
Affinity DataIC50: 575nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent