BDBM191353 US9670203, Compound 2.12 1-((1S,1aS,6bS)-5-((9H-purin-6-yl)oxy)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-1-yl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)urea
SMILES C[Si](C)(C)CCOCn1cnc2c(Oc3ccc4O[C@@H]5[C@@H](NC(=O)Nc6ccc(F)c(c6)C(F)(F)F)[C@@H]5c4c3)ncnc12
InChI Key InChIKey=GSHFRVCWJNQUTO-FIXSFTCYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 191353
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair