BDBM191487 US9181272, 257::US9181272, 268::US9181272, 269

SMILES CS(=O)(=O)N1CCCC1c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O

InChI Key InChIKey=YSLWSENALYBHTH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 191487   

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191487(US9181272, 268 | US9181272, 269 | US9181272, 257)
Affinity DataIC50: 16.5nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191487(US9181272, 268 | US9181272, 269 | US9181272, 257)
Affinity DataIC50: 18.4nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent

TargetCytochrome P450 family 11 subfamily B member 2(Green monkey)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM191487(US9181272, 268 | US9181272, 269 | US9181272, 257)
Affinity DataIC50: 34.6nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2016
Entry Details
US Patent