BDBM192401 US9187462, II-11

SMILES COc1ccc(cc1F)[C@H](NC(=O)c1cc(F)c2cnc(NCCC#N)nc2c1)c1cnn(C)c1

InChI Key InChIKey=NBXOSGJMUZEDBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192401   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM192401(US9187462, II-11)
Affinity DataIC50: 13.9nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent