BDBM192390 BDBM192405::US9187462, I-70::US9187462, II-15

SMILES COc1ccc(cc1F)[C@H](NC(=O)c1cc(F)c2cnc(N[C@@H]3CCOC[C@@H]3F)nc2c1)c1cnn(C)c1

InChI Key InChIKey=YHZOHYDIEKONRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192390   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM192390(US9187462, II-15 | US9187462, I-70 | BDBM192405)
Affinity DataIC50: 4nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM192390(US9187462, II-15 | US9187462, I-70 | BDBM192405)
Affinity DataIC50: 4.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent