BDBM192414 US9187462, II-24

SMILES Cc1cc(Nc2ncc3ccc(cc3n2)C(=O)N[C@H](c2cnn(C)c2)c2ccc(Cl)c(F)c2)n(C)n1

InChI Key InChIKey=WRBFTHCJJMVCDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192414   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM192414(US9187462, II-24)
Affinity DataIC50: 14.6nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
Go to US Patent