BDBM192918 US10526329, Compound 132::US9670204, 132 1-(4-(2-ethyl-3-((4-(4-fluorophenyl)thiazol-2-yl)(methyl)amino)imidazo[1,2-a]pyridin-6-yl)piperidin-1-yl)-3-(methylamino)propan-1-one

SMILES CCc1nc2ccc(cn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)C1CCN(CC1)C(=O)CCNC

InChI Key InChIKey=RHXMUBRTNRIDQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 192918   

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM192918(US9670204, 132 1-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 1.00E+3nMpH: 8.5 T: 2°CAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate. 5 μL of a di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
US Patent

TargetAutotaxin(Human)
Galapagos

US Patent
LigandPNGBDBM192918(US9670204, 132 1-(4-(2-ethyl-3-((4-(4-fluorophenyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2020
Entry Details
US Patent