BDBM193084 (S)-3-((S)-3-(((1R,5S,6S)-3-(5-((1R,3R)-2- (2,2-difluoroethyl)-3-methyl-2,3,4,9- tetrahydro-1H-pyrido[3,4-b]indol-1- yl)pyrimidin-2-yl)-3- azabicyclo[3.1.0]hexan-6-yl)methyl)-8- oxo-1,2,3,4,4a,5,8,10-octahydro-9H- pyrazino[1',2':4,5][1,4]oxazino[2,3- f]isoindol-9-yl)piperidine-2,6-dione::US20260007681, Compound A4

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2cnc(N3C[C@@H]4[C@@H](CN5CCN6c7cc8c(cc7OC[C@@H]6C5)C(=O)N(C5CCC(=O)NC5=O)C8)[C@@H]4C3)nc2)N1CC(F)F

InChI Key InChIKey=XWLHEKLYOZIHSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193084   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 193084BDBM193084((S)-3-((S)-3-(((1R,5S,6S)-3-(5-((1R,3R)-2- (2,2-di...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent