BDBM194334 US9200016, 16::US9902710, Compound 16

SMILES CCn1ncc2c(Cl)c(Cc3cncc4cc(OC)c(OC)cc34)cnc12

InChI Key InChIKey=HOCYBZBWBKOFQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194334   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Exonhit Therapeutics

US Patent
LigandPNGBDBM194334(US9200016, 16 | US9902710, Compound 16)
Affinity DataIC50: 330nMAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Exonhit Therapeutics

US Patent
LigandPNGBDBM194334(US9200016, 16 | US9902710, Compound 16)
Affinity DataIC50: 330nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent