BDBM194439 US9200016, 121::US9902710, Compound 121

SMILES CCCc1ncc(Cc2ccc3cccc(OCc4nnn[nH]4)c3n2)c2cc(OC)c(OC)cc12

InChI Key InChIKey=KJNUIMPGLAXPDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194439   

LigandPNGBDBM194439(US9200016, 121 | US9902710, Compound 121)
Affinity DataIC50: 4.70nMpH: 7.4 T: 2°CAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

LigandPNGBDBM194439(US9200016, 121 | US9902710, Compound 121)
Affinity DataIC50: 4.70nMAssay Description:The phosphodiesterase assay was developed using the LANCE cAMP kit (PerkinElmer). The assay buffer contained HBSS with 5 mM HEPES, 0.1% BSA, and 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent