BDBM195073 US9212153, 132,Ex. 97

SMILES COC1CCC2(CC1)Oc1ccc(OCC3CC3)cc1C21N=C(N)N(C)C1=O

InChI Key InChIKey=OIMHOXZSLOPGKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195073   

TargetBeta-secretase 1 [1-458](Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM195073(US9212153, 132,Ex. 97)
Affinity DataIC50: 24.9nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
US Patent