BDBM195177 US9212153, 239,Ex. 196

SMILES COC1CCC2(Cc3ccc(OC4CC4)cc3C22N=C(N)N(C)C2=O)CC1

InChI Key InChIKey=PAJIOZYNQUNKPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195177   

TargetBeta-secretase 1 [1-458](Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM195177(US9212153, 239,Ex. 196)
Affinity DataIC50: 29.3nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
Go to US Patent