BDBM199021 BDBM199022::BDBM199028::BDBM199029::BDBM199030::BDBM199031::US9221832, 85

SMILES CC(C(=O)NC1COc2ncccc12)c1ccc(Cl)cc1Cl

InChI Key InChIKey=WJPNUTYLRJIVMN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 199021   

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 15nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 33nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 9nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 137nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 11nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetP2X purinoceptor 7(Human)
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM199021(BDBM199022 | BDBM199029 | BDBM199028 | US9221832, ...)
Affinity DataIC50: 104nMAssay Description:Cell line generation was performed in general according to established molecular cloning protocols. Specifically, RNA was extracted from human whole ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent