BDBM19910 3-arylquinazolinone, 1aa::5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one

SMILES Oc1ccc(cc1)-n1cnc2cc(O)cc(O)c2c1=O

InChI Key InChIKey=VIZPQPBPYLOQMH-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19910   

TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19910(5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquina...)
Affinity DataIC50: 1.11E+4nM EC50:  2.92E+3nMpH: 8.0 T: 2°CAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19910(5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydroquina...)
Affinity DataIC50: 179nM EC50:  76nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed