BDBM199277 US9221808, 1ck

SMILES COc1ccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)cc1OC

InChI Key InChIKey=WYXUUYVDGIFLQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199277   

TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199277(US9221808, 1ck)
Affinity DataIC50: 2.50E+4nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199277(US9221808, 1ck)
Affinity DataIC50: 4.51E+4nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent