BDBM20068 5-Substituted-6-chlorouracil, 10d::6-chloro-5-(4-fluorophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

SMILES O=c1[nH]c(Cl)c(-c2ccc(F)cc2)c(=O)[nH]1

InChI Key InChIKey=MCYVCRAEPLBWQR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20068   

TargetThymidine phosphorylase(Human)
Gilead Sciences

LigandChemical structure of BindingDB Monomer ID 20068BDBM20068(6-chloro-5-(4-fluorophenyl)-1,2,3,4-tetrahydropyri...)
Affinity DataKi:  710nM ΔG°:  -8.72kcal/molepH: 6.4 T: 2°CAssay Description:The enzyme reaction was started by the addition of enzyme to the reaction mixture containing substrate and test compounds. The reaction was stopped b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2008
Entry Details Article
PubMed