BDBM20095 dipeptide-derived nitrile, 16::tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-phenylethyl]carbamate
SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#N
InChI Key InChIKey=OYGWLRRBJCSNDB-ZDUSSCGKSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 20095
Affinity DataKi: 260nM ΔG°: -8.98kcal/molepH: 6.5 T: 2°CAssay Description:Enzyme activities were calculated from kinetic measurements performed by spectrophotometric detection of the product p-nitroaniline (pNA) at waveleng...More data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 2.51E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
Affinity DataKi: 4.10E+3nMAssay Description:Enzyme activities were calculated from kinetic measurements performed by fluorimetric detection of the product AMC at the wavelengths for excitation ...More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+4nMpH: 6.0Assay Description:Inhibition of human liver cathepsin B using Cbz-Arg-Arg-pNA as substrate at pH 6 incubated for 30 mins measured for 20 mins by photometrical analysisMore data for this Ligand-Target Pair