BDBM201247 US9187424, 15-1::US9187424, 15-2

SMILES COc1ccc(cc1)C1=C[C@](NC(=O)C1(F)C#N)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key InChIKey=BHSJXNNODPQRCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 201247   

LigandPNGBDBM201247(US9187424, 15-2 | US9187424, 15-1)
Affinity DataIC50: 12nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

LigandPNGBDBM201247(US9187424, 15-2 | US9187424, 15-1)
Affinity DataIC50: 431nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

LigandPNGBDBM201247(US9187424, 15-2 | US9187424, 15-1)
Affinity DataIC50: 3.31E+3nMpH: 7.4 T: 2°CAssay Description:MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent

LigandPNGBDBM201247(US9187424, 15-2 | US9187424, 15-1)
Affinity DataIC50: 3.33E+4nMpH: 7.4 T: 2°CAssay Description:MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2016
Entry Details
US Patent