BDBM202069 US9233981, 31

SMILES NC1=N[C@]2(CO[C@H](C[C@H]2CS1)c1ccc(cc1)C(F)F)c1ccc(F)cc1F

InChI Key InChIKey=ZLRRMYNTUCHQJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202069   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM202069(US9233981, 31)
Affinity DataIC50: 28nMpH: 4.5 T: 2°CAssay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
US Patent