BDBM20351 3-{[4-(azepan-1-yl)-3-fluorophenyl]methyl}-1-isoquinolin-5-ylurea::Isoquinoline Analogue, 45

SMILES Fc1cc(CNC(=O)Nc2cccc3cnccc23)ccc1N1CCCCCC1

InChI Key InChIKey=FGHMUMXBRABSJJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20351   

LigandPNGBDBM20351(3-{[4-(azepan-1-yl)-3-fluorophenyl]methyl}-1-isoqu...)
Affinity DataEC50:  2.80nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2008
Entry Details Article
PubMed