BDBM203757 US9221809, 308::US9221809, 341

SMILES Cc1ccc2sc(nc2c1)-c1c(N[C@@H]2CCCNC2)nc([nH]c1=O)N1CCOCC1

InChI Key InChIKey=TZUXTMLEAKQRKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 203757   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203757(US9221809, 341 | US9221809, 308)
Affinity DataIC50: 120nMpH: 7.2 T: 2°CAssay Description:A 20 ul reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (RP7030, Molecular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203757(US9221809, 341 | US9221809, 308)
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:A 20 ul reaction mixture contains 10 mM TriHCl, pH 7.2, 0.5 nM GST tagged IRAK4 (SignalChem), 100 nM fluorescent peptide substrate (RP7030, Molecular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details
US Patent