BDBM204020 US9242996, 142

SMILES Nc1ncc(nc1-c1ccc(C(=O)N[C@H](CO)c2ccccc2)c(F)c1)-c1ccncc1

InChI Key InChIKey=PTDAVSTWSKJTOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204020   

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM204020(US9242996, 142)
Affinity DataIC50: 0.210nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM204020(US9242996, 142)
Affinity DataIC50: 0.201nMpH: 7.5Assay Description:Compound potency against activated ERK2 is determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2016
Entry Details
US Patent