BDBM204110 US9539260, H11::US9539260, H12::US9763952, Example H12

SMILES COc1ncc(cc1F)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCS(=O)(=O)C3)cc12

InChI Key InChIKey=GXDRASGLDDVQKO-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 204110   

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
In Depth
Date in BDB:
7/26/2019
Entry Details
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LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 7nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 8nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
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LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 299nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 299nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 471nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 530nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2019
Entry Details
Go to US Patent

LigandPNGBDBM204110(US9539260, H12 | US9539260, H11 | US9763952, Examp...)
Affinity DataIC50: 530nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details
Go to US Patent