BDBM206142 US9255110, 55

SMILES O=C(Nc1cc2ccccc2cc1OC1CCC(O)CC1)c1cnn2cccnc12

InChI Key InChIKey=FQVCSBNTPQDQSS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206142   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 206142BDBM206142(US9255110, 55)
Affinity DataIC50: 124nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 206142BDBM206142(US9255110, 55)
Affinity DataIC50: 628nMpH: 7.2 T: 2°CAssay Description:SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 206142BDBM206142(US9255110, 55)
Affinity DataIC50: 817nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details
US Patent