BDBM206767 (R)-3-((S)-7-((1-(6-((1R,3S)-3-methyl-2- (2,2,2-trifluoroethyl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indol-1-yl)pyridin-3- yl)piperidin-4-yl)methyl)-1-oxo- 1,3,5,5a,6,7,8,9-octahydro-2H- pyrazino[1',2':4,5][1,4]oxazino[2,3- e]isoindol-2-yl)piperidine-2,6-dione::US20260007681, Compound A62

SMILES C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2ccc(N3CCC(CN4CCN5c6ccc7c(c6OC[C@@H]5C4)CN([C@@H]4CCC(=O)NC4=O)C7=O)CC3)cn2)N1CC(F)(F)F

InChI Key InChIKey=HAYVMVVVUBVUSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206767   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 206767BDBM206767((R)-3-((S)-7-((1-(6-((1R,3S)-3-methyl-2- (2,2,2-tr...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent