BDBM206795 US9249163, 93

SMILES C1CN(CCO1)c1ncc(-c2cnc3nc[nH]c3c2)n2cc(\C=C\c3ccc4ccccc4n3)nc12

InChI Key InChIKey=YJLCFMJRYGPXHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206795   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM206795(US9249163, 93)
Affinity DataIC50: 10nMpH: 7.8Assay Description:Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM206795(US9249163, 93)
Affinity DataIC50: 13nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6×Hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
Go to US Patent