BDBM207559 US10501467, Example 4::US9260440, 4::US9617273, Example 4

SMILES CC1(C)CCc2[nH]c3cccc4c3c2c1n[nH]c4=O

InChI Key InChIKey=WCAMYOIGSKFYKH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 207559   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  18.6nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  1.05E+3nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  1.05E+6nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  1.05E+6nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  1.86E+4nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207559(US10501467, Example 4 | US9260440, 4 | US9617273, ...)
Affinity DataIC50:  1.86E+4nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent