BDBM207605 US10501467, Example 50::US9260440, 50::US9617273, Example 50

SMILES CN(C)CCn1c2c3c4c(cc(F)cc41)C(=O)NN=C3CN(C(=O)C1CC1)C2

InChI Key InChIKey=FQNVRHRLGXDLDH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 207605   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207605BDBM207605(US9260440, 50 | US9617273, Example 50 | US10501467...)
Affinity DataIC50: 18nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207605BDBM207605(US9260440, 50 | US9617273, Example 50 | US10501467...)
Affinity DataIC50: 18nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 207605BDBM207605(US9260440, 50 | US9617273, Example 50 | US10501467...)
Affinity DataIC50: 1.80E+4nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent