BDBM209853 US9273052, 1::US9566277, 1

SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key InChIKey=YKRHDVRJUDSJQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209853   

TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209853(US9273052, 1 | US9566277, 1)
Affinity DataIC50: 15nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209853(US9273052, 1 | US9566277, 1)
Affinity DataIC50: 15nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent